Recombinant TSH (Thyrogen®) for ablation of thyroid remnant tissue post-thyroidectomy for thyroid cancer
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چکیده
• I ablation of remnant thyroid tissue following a total or near-total thyroidectomy for thyroid cancer is carried out in the hypothyroid state to increase endogenous TSH release and thus promote uptake of radioodine into the remaining thyroid tissue. Usually thyroid replacement therapy has to be withheld from patients for 3 to 6 weeks before ablation in order to achieve an adequate TSH level. This can have a profound negative effect on the patient’s quality of life.
منابع مشابه
Recombinant human thyroid stimulating hormone in 2008: focus on thyroid cancer management
Radioiodine (RAI) ablation following thyroidectomy is standard of care treatment for patients with intermediate or high risk differentiated thyroid cancer. Traditionally, this has been achieved by forgoing thyroid hormone replacement postoperatively, allowing endogenous thyroid stimulating hormone (TSH) levels to rise. This rise in TSH provides the stimulus for RAI uptake by the thyroid remnant...
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